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A non-canonical R-loop resolving function of PIWIL4 maintains the genomic integrity and leukemic growth of AML cells

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE188490
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PIWIL4 enzyme is required for resolving R-loops and for growth of AML cells. We examine the impact of PIWIL4 knockdown and R-loop accumulation on gene expression in AML cell line THP-1 Examination of differential gene expression upon PIWIL4 knockdown in AML cells
创建时间:
2023-05-29
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