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CDKN1A is a target for phagocytosis-mediated cellular immunotherapy in acute leukemia

ChEBI2022-10-25 更新2026-07-12 收录

白血病免疫治疗

细胞吞噬靶点研究

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-12280 数据链接链接失效反馈

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CDKN1A is a target for phagocytosis-mediated cellular immunotherapy in acute leukemia

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2022-10-25

表观遗传调控

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Acute myeloid leukemia cell lines were treated with the hypomethylating agent decitabine and interferon gamma to investigate if these treatments induce HLA II gene expression. Cells carrying either co

NIAID Data Ecosystem100

LV-Induced Dendritic Cells for AML Immunotherapy

白血病免疫治疗

树突状细胞疫苗

Wilms’ tumor 1 antigen (WT1) is overexpressed in acute myeloid leukemia (AML). Unfortunately, clinical immunotherapeutic use of WT1 peptides against AML has been inconclusive. A tricistronic lentivira

NIAID Data Ecosystem40

Lip-1 induces cell cycle arrest, apoptosis, and pyroptosis in K562 cells

白血病免疫治疗

细胞死亡机制

summary (1)Objective: To investigate the antileukemic role of Lip-1 in K562 leukemia cells. (2)Methods: We performed CCK-8, flow cytometry, microscopy, western blotting assay, next generation sequen

NIAID Data Ecosystem30

Single-cell CML TKI stop

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单细胞免疫组学

Update 2/26! We also have data related to dasatinib+IFN-a in CML (Huuhtanen et al., JCI) in a different Zenodo:https://zenodo.org/records/10947495https://www.jci.org/articles/view/152585______________

Zenodo2026-02-20 更新50

mRNA expression profile of Lymphocytes by high-throuput sequencing. Homo sapiens

白血病免疫治疗

T细胞编程

The activation of CD4+ T helper (Th) cells is crucial for the induction of cytotoxic T lymphocyte (CTL) responses against malignancy. We reprogrammed a Th clone specific for chronic myelogenous leukem

NIAID Data Ecosystem30

CDKN1A is a target for phagocytosis-mediated cellular immunotherapy in acute leukemia

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