Diminished IgV diversification after overexpression of Ung2 in DT40 cells

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Diminished IgV diversification after overexpression of Ung2 in DT40 cells. The frequency of sIgM-loss cells was compared in AID-reconstituted sIgM+ jV- AID-/- DT40 cells after overexpression of either mUng2 (mUng2/AIDR) or an empty control (AIDR). Untransduced cells are shown (-). 12 independent clones for each sample were analyzed after 31 days of clonal expansion.

创建时间：

2024-04-01