Differential miroRNA expression in myostatin knockout mice

To identify microRNAs involved in myostatin-deficient muscular hypertrophy, we compared miRNA expression in wild-type and myostatin knockout mice. Total RNA, isolated from three wild-type or myostatin knockout mice, was pooled and then used for microarray analysis.为鉴定参与肌抑素缺失型肌肉肥大的微小核糖核酸（microRNAs），我们对比了野生型与肌抑素敲除小鼠的微小核糖核酸表达情况。从3只野生型或肌抑素敲除小鼠中提取的总核糖核酸（Total RNA）经混合后，用于微阵列分析（microarray analysis）。