PIP4K2B immunoprecipitation and mass spectrometry to identify interactors

phosphatidylinositide kinases (PIPKs) catalyze the formation of PtdIns(4,5)P2. Type II PIPKs comprises PIP4K2a, PIP4K2b and PIP4K2c. Type II PIPKs regulate insulin signaling, glucose metabolism, autophagy, sense cellular GTP concentration. In this study, we have investigated the role of PIP4K2A and PIP4K2B in transcriptional response post genotoxic stress..