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A Useful Synthetic Equivalent of a Hydroxyacetone Enolate

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https://figshare.com/articles/dataset/A_Useful_Synthetic_Equivalent_of_a_Hydroxyacetone_Enolate/2618650
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Indium promoted allylation of carbonyl compounds with 4-(bromomethyl)-1,3-dioxol-2-one diastereoselectively affords anti-α,β-dihydroxyketones, protected as enol carbonates. These initial products can be deprotected to free dihydroxyketones or transformed under mild conditions into the corresponding cyclic carbonates, which constitutes a useful approach to hydroxyacetone aldols.
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2016-02-23
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