Cobalt-Catalyzed Oxidative Cyclization of Benzamides with Maleimides: Synthesis of Isoindolone Spirosuccinimides
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https://figshare.com/articles/dataset/Cobalt-Catalyzed_Oxidative_Cyclization_of_Benzamides_with_Maleimides_Synthesis_of_Isoindolone_Spirosuccinimides/5510032
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资源简介：
The
oxidative cyclization of substituted benzamides with maleimides
assisted by 8-aminoquinoline in the presence of a catalytic amount
of Co(OAc)2·4H2O provides isoindolone spirosuccinimides
in good to excellent yields. The cyclization reaction was compatible
with various substituted benzamides and maleimides. A possible reaction
mechanism involving the C–H bond activation as a key step was
proposed. The competition experiment and deuterium labeling studies
were performed to investigate the mechanism of the reaction.
创建时间：
2017-10-18
