In vivo emergence of Imipenem/relebactam resistance in KPC-producing Klebsiella pneumoniae mediated by increased blaKPC copy number and porins
收藏NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA794363
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资源简介：
In this study we characterized three Klebsiella pneumoniae strains isolated from patients with different bloodstream infection (BSI) episodes. Strains evolved from imipenem/relebactam susceptibility to resistance during antimicrobial treatment. Genomic analysis demonstrated that imipenem/relebactam resistance was associated to duplication of Tn4401 transposon and subsequently blaKPC copy number increased.
创建时间：
2022-01-05
