Global Gene Expression Changes in Cholangiocytes Treated with P300 inhibitor SGC-CBP30 (10 μM; Selleckchem, #S7256)
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE168174
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资源简介：
Histone modification is a critical epigenetic regulatory mechanism that is under-explored in cholestatic liver disease. Lysine 27 on histone 3 (H3K27) is a key regulatory residue that can be acetylated by the histone acetyltransferase (HAT) p300, which acts as a transcriptional coactivator. Cholangiocyte cell line, HiBEC, were treated with DMSO or SGC-CBP30 (10uM) to look at the gene expression changes due to pharmacological inhibition of P300
创建时间：
2021-04-30
