Ets1 modulates epigentic landscape of key TFH genes in T naïve cells
收藏NIAID Data Ecosystem2026-05-26 收录
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资源简介：
Ets1 can directly bind key TFH genes, regulating their expression . Loss of Ets1 results in the pre-mature expression of TFH-genes in Non-TFH cells. We wished to analyze if loss of Ets1 correlated with changes in chromatin accessibility especially in TFH gene loci. Overall design: DNA was extracted from splenic CD4+CXCR5+PD-1+ TFH and CD4+CD44-CD62L+ T naïve cells in Ets1 fl/fl and CD4-cre Ets1 fl/fl mice and analyzed by ATAC seq.
创建时间：
2019-03-04
