Electrospun Fibres of Polyhydroxyalkanoate/Bacterial Cellulose blends and their role in Nerve Tissue Engineering

This study involved the development of novel blend electrospun nanofibres through the combination of short-chain length polyhydroxyalkanoates (SCL-PHAs), medium-chain length polyhydroxyalkanoates (MCL-PHAs), and bacterial cellulose (BC) using the electrospinning technique. The resultant fibrous materials were characterised for their thermal properties, morphology, and cytocompatibility with NG108-15 neuronal cells. The incorporation of BC into the blend significantly enhanced the thermal stability of the polymer matrix, as evidenced by thermogravimetric analysis.