Comprehensive bulk RNAseq analysis on whole kidneys during regeneration and fibrosis development reveals sustained dysregulation of immune system related pathways during kidney fibrosis. Comprehensive bulk RNAseq analysis on whole kidneys during regeneration and fibrosis development reveals sustained dysregulation of immune system related pathways during kidney fibrosis

In order to identify the transcriptional changes that correlate with kidney regeneration or fibrosis development, we performed a time-course bulk RNA-seq from whole-kidneys at 3, 7, 14, 28 and 42 days after the initial ischemic kidney from two distinct murine models.