Regionalpcs ROSMAP Differential Methylation Results
收藏资源简介：
This dataset contains differential methylation results for the manuscript titled "regionalpcs improve discovery of DNA methylation associations with complex traits" Tiffany Eulalio*1, Min Woo Sun1, Olivier Gevaert1, Michael D. Greicius2, Thomas J. Montine3, Daniel Nachun*‡3, Stephen B. Montgomery*‡1,3 ‡ These authors contributed equally as senior authors * Corresponding authors: Tiffany Eulalio (eulalio@alumn.stanford.edu), Daniel Nachun (dnachun@stanford.edu), Stephen B. Montgomery (smontgom@stanford.edu) Author affiliations: 1. Department of Biomedical Data Science, Stanford University, Stanford, CA 2. Department of Neurology & Neurological Sciences, Stanford University, Stanford, CA 3. Department of Pathology, Stanford University, Stanford, CA Dataset description: Differential methylation analyses were performed using methylation summarized as averages, regional PCs, and CpGs across multiple gene regions: full gene region, gene body, preTSS, and promoters. Files are named according to the gene region: [gene region]_full_DM_results.csv: Comprehensive differential methylation results. [gene region]_all_counts.csv: Summarized counts of significant differential methylation results.
