Expression of 97 surface markers and 462 mRNAs in 70017 cells from healthy young, healthy old and leukemic human bone marrow

Seurat v3 object <b><br></b><b>ASSAYS</b>:AB: Antibody expression dataRNA: mRNA expression dataintegrated: Antibody and mRNA expression matrices were concatenated and data was integrated across patients using scanorama<br><b>DIMENSIONALITY REDUCTION</b>MOFA: Multi-OMICS factor analysis to integrate AB and RNA data. MOFA was run on scanorama-integrated data and served as input for clustering and further dimensionality reduction.MOFAUMAP: UMAP performed on MOFA dimensions. Display used in the manuscript.<br>MOFATSNE: UMAP performed on MOFA dimensions.<br><br><b>METADATA</b>Batch: Source individual (BM1-3, Aged1-3, AML1, AML3 and Q59. Q59 is called AML2 in the manuscript).class: Type of individual (healthy young, healthy old or AML).