Comparison of control and experimental groups.

The number of macroscopic lesions detectable by bioluminescence imaging in the left tibia was similar between control animals that did not undergo clot induction and experimental animals with a blood clot in which cancer cells were injected 1 minute prior to (−1 min), or 5 minutes after clot induction (+5 min). Data from all mice (including those that already died) 7 weeks after cancer cell injection are shown. Data were analyzed using Fisher's exact test and no significant differences were detected in the CT/experimental group pairs. *The percentage presented is calculated as follows: number of lesions at a specific site/total number of lesions in the group.