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Interactions of melanoma cells with distal keratinocytes trigger metastasis via Notch signaling inhibition of MITF

ChEBI2015-07-30 更新2026-07-12 收录

黑色素瘤转移

Notch信号通路

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-69403 数据链接链接失效反馈

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资源简介：

Interactions of melanoma cells with distal keratinocytes trigger metastasis via Notch signaling inhibition of MITF

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创建时间：

2015-07-30

黑色素瘤转移

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Notch ligand Dll4 impairs the recruitment of hemogenic cells into intra-aortic clusters and limits hematopoietic stem cell production

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Hematopoietic stem cells (HSCs) develop from the hemogenic endothelium in the embryonic aorta. In most vertebrates, hemogenic cells protrude into the aortic lumen forming clusters where the hematopoie

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Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques [Rec1_ChIP-seq]

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Purpose: To investigate the impact of oncogenic Notch on the 3D genome organization of cancer cells. Methods: We generated cohesin HiChIP and 1D epigenomic data sets in two different Notch-dependent c

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Supplementary Materials for JAADI-D-25-00322R1

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This is the Supplementary Materials for Predicting sentinel lymph node metastasis in melanoma patients: A machine learning-based predictive model, including Supplementary Methonds, Figures, Figure leg

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Sequential ligand-dependent Notch signaling activation regulates valve primordium formation and morphogenesis

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Our studies identify a mechanism of signaling crosstalk during valve morphogenesis that sheds light on the origin of congenital heart defects associated with reduced Notch function. Aortic and pulmona

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Interactions of melanoma cells with distal keratinocytes trigger metastasis via Notch signaling inhibition of MITF

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