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Vitamin C promotes oligodendrocytes generation and remyelination

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干细胞与再生医学数据中心2021-09-08 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=db041ecea81f475c993751b6c823e057
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1.Identify inducers of OPC to OL differentiation through high-throughput screening(As-2P);2.As-2P promotes OPC to OL differentiation;3.facilitates the formation of myelin sheaths in OPC-neuron co-culture in vitro;4.promotes myelin regeneration in a cuprizone-mediated demyelination model;5.A number of reported antioxidants were also tested in the OPC differentiation assay, and results indicate that As-2P’s effect in promoting OPC to OL differentiation might be independent of its antioxidant properties.
提供机构:
同济大学
创建时间:
2021-09-08
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