Crystal structure of PI3K-gamma in complex with a quinoline inhibitor
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Crystal structure of PI3K-gamma in complex with a quinoline inhibitor Descriptor: N-{2-chloro-5-[4-(morpholin-4-yl)quinolin-6-yl]pyridin-3-yl}-4-fluorobenzenesulfonamide, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION Authors: Whittington, D.A, Tang, J, Yakowec, P. Deposit date: 2011-05-16 Release date: 2011-06-08 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Phospshoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitors: Discovery and Structure-Activity Relationships of a Series of Quinoline and Quinoxaline Derivatives. J.Med.Chem., 54, 2011
创建时间：
2011-05-16
