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Lysine methyltransferase SETD6 modifies histones on a glycine-lysine motif

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DataCite Commons2020-08-26 更新2024-07-27 收录
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https://tandf.figshare.com/articles/Lysine_methyltransferase_SETD6_modifies_histones_on_a_glycine-lysine_motif/9210062/1
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资源简介:
Although central to regulating the access to genetic information, most lysine methyltransferases remain poorly characterised relative to other family of enzymes. Herein, I report new substrates for the lysine methyltransferase SETD6. Based on the SETD6-catalysed site on the histone variant H2AZ, I identified similar sequences in the canonical histones H2A, H3, and H4 that are modified by SETD6 <i>in vitro</i>, and putative non-histone substrates. I herein expend the repertoire of substrates for methylation by SETD6.
提供机构:
Taylor & Francis
创建时间:
2019-08-02
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