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Gene expression changes in primary Sertoli cells treated with MEK1/2 inhibitor

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE41645
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To investigate the gene expression regualted by MEK1/2-ERK1/2 signaling in Sertoli cells, we cultured primary Seroli cells and treated bFGF and PD0325901, which are activator and inhibitor of the signaling, respectively. Isolated primary Sertoli cells were incubated with 20ng bFGF, 10uM PD0325901 or vehicle for 24 hours and then gene expression changes were measured with microarray analysis
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2024-02-29
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