Genomic substitutions present in the consensus sequence of the populations obtained upon evolution of Qβ0 at constant and deterministically fluctuating temperatures.

1Protein encoded by the gene where the nucleotide substitution indicated is located.2Amino acid replacement produced by the nucleotide change. In the cases where no amino acid change is indicated, the substitution is synonymous.3Number of populations where a given substitution appears either fixed or as a polymorphism.