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Crystal Structure of 12 bound to CK2a

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Protein Data Bank Japan2026-05-27 更新2026-06-30 收录
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Crystal Structure of 12 bound to CK2a Descriptor: (4P)-3-{[3-({N-[(2-chloro[1,1'-biphenyl]-4-yl)methyl]-beta-alanyl}amino)propyl]amino}-4-(1H-pyrazol-5-yl)benzoic acid, ACETATE ION, Casein kinase II subunit alpha Authors: Brear, P, Glossop, P, Pandey, S, Hyvonen, M, Spring, D, Butt, R, Cawkill, D. Deposit date: 2025-03-12 Release date: 2026-01-14 Last modified: 2026-05-27 Method: X-RAY DIFFRACTION (1.28 Å) Cite: Exploiting the Cryptic alpha D Pocket of Casein Kinase 2 alpha (CK2 alpha ) to Deliver Highly Potent and Selective Type 1 Inhibitors. J.Med.Chem., 68, 2025
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2025-03-12
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