Myxococcus xanthus cells: wild-type vs. EBP mutant gene expression during development. Myxococcus xanthus

The mutants in our study carry an insertion in the nla4 (MXAN2516), nla6 (MXAN4042), nla18 (MXAN3692) or nla28 (MXAN1167) gene. (MXAN numbers are the conventional gene names; nlas are common names). Mutations in the nla genes produce strong defects in fruiting body development. All four of the nla genes code for enhancer binding proteins (EBPs), which are transcriptional activators. In this study, we examined how the nla mutations alter gene expression patterns in developing cells. Overall design: Two condition experiment, normal wild-type vs mutant