Access to Carbonyl Azides via Iodine(III)-Mediated Cross-Coupling

Herein, we present
a prominent metal-free C–N
cross-coupling
platform that enables access to carbamoyl- and ketoazides from isocyanides
or silyl enol ethers and trimethylsilyl azide (TMSN3) with
an aid of iodine(III) promoter. This offers a rapid route to a diverse
set of synthetically valuable azide decorated fragments with excellent
substrate scope and good to excellent yields. The disclosed platform
exemplifies the use of TMSN3 for incorporation of the azide
fragment without the loss of N2.