P38 in complex with Sorafenib
收藏Protein Data Bank Japan2023-09-06 更新2026-03-21 收录
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https://pdbj.org/mine/summary/3heg
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P38 in complex with Sorafenib Descriptor: 4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE, Mitogen-activated protein kinase 14 Authors: Namboodiri, H.V, Karpusas, M. Deposit date: 2009-05-08 Release date: 2009-11-10 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Analysis of imatinib and sorafenib binding to p38alpha compared with c-Abl and b-Raf provides structural insights for understanding the selectivity of inhibitors targeting the DFG-out form of protein kinases. Biochemistry, 49, 2010
创建时间：
2009-05-08
