Intestinal microbiota after sleep deprivation and intervention in mice

The experiment was divided into four groups: blank control group (CON), chronic unpredictable mild stress (CSD) group, Liuwei Anshen Capsule group (LWAS), and Zopiclone group (ZPKL). The CON group was given normal feeding and sterile water gavage; The CSD group was subjected to chronic sleep deprivation modeling and sterile water gavage; The LWAS group was subjected to chronic sleep deprivation modeling and gavage of Liuwei Anshen capsules; The ZPKL group was subjected to chronic sleep deprivation modeling and gastric lavage with zopiclone tablets.