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资源简介：
Analysis of human Immunoglobuline genes repertoire of B cell in peripheral blood from healthy donors
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创建时间：
2020-04-17
相关数据集
Supplementary Material for: Postnatal and Adult Immunoglobulin Repertoires of Innate-Like CD19 + CD45R lo B Cells
The diversity in antibody repertoire relies on different B cell populations working efficiently to fulfil distinct specific functions. We recently described an innate-like CD19+CD45R-/lo (19+45Rlo) ce
NIAID Data Ecosystem160
H3K36 methyltransferase NSD1 is essential for normal B1 and B2 cell development and germinal center formation. H3K36 methyltransferase NSD1 is essential for normal B1 and B2 cell development and germinal center formation
This study aims to illustrate the effect of H3K36 methyltransferase NSD1 in B2 cells. Overall design: Comparative gene expression profiling analysis of RNA-seq data for WT B220+ B cells (Mb1-Cre+ NSD1
NIAID Data Ecosystem70
ZBTB38 is dispensable for hematopoiesis and antibody responses.. ZBTB38 is dispensable for hematopoiesis and antibody responses.
We performed RNA-sequencing of ZBTB38-sufficient and -deficient germinal center B cells. Very few genes were dysregulated by the absence of ZBTB38. Overall design: RNA-seq of ZBTB38 KO and WT germinal
NIAID Data Ecosystem40
Loss of TET2 results in DNA methylation changes in mouse GC B-cells (hMeDIP-Seq data set)
Absence of Tet2 at mouse cells results in loss of hydroxymethylcytosine Hydroxymethylmethylcytosine DNA immunoprecipitation sequencing (hMeDIP-seq) of mouse TET2 WT and KO GC B-cells
NIAID Data Ecosystem80
Individualized Ig V gene allele databases for RSb17.
The sequences of germline alleles were inferred using the individual database by means of the IgDiscover algorithm [16] and a database from [3]. (TXT)
NIAID Data Ecosystem60
