Summary of humoral and cell-mediated responses against MAP according to histopathological findings.

MAP presence was assessed by tissue culture and rtPCR. Paratuberculosis specific antibodies detected by ELISA (AB) and IFN-γ release assay (IGRA) after blank stimulation (PBS) and stimulation with avian (PPDAV) and bovine antigens (PPDBOV) are shown as mean optical density (OD) values and standard error (SE). Statistical significance (Student t-test): *p