ESBL Phosphoproteomic Data - Web Archive

The Epithelial Systems Biology Laboratory (DIR,NHLBI,NIH), headed by Mark Knepper, has developed a number of databases archiving previously published proteomic data in kidney and have made them available to the community. The .zip file contains web architecture for access to "Phosphoproteomic Data". Full documentation is included on the various pages. The various links allow users to access databases with capability to search, browse or download data sets. Please see https://esbl.nhlbi.nih.gov/Databases/KSBP2/Targets/Phosphoproteomics.html for current implementation as of April 9, 2026. The following elements are included:1. mpkCCD Phosphoproteome: Response to Vasopressin (Datta et al., 2021)2. Rat IMCD Phosphoproteome: Steady State Response to Vasopressin (Deshpande et al., 2019)3. Consensus Vasopressin-Regulated Phosphorylation Sites in Collecting Duct4. Vasopressin-Regulated Phosphorylation Sites Mapped to Cell-Level Actions of Vasopressin5. Rat IMCD Phosphoproteome: Time Course of Response to Vasopressin (TMT) (Leo et al., 2022)6. Rat IMCD Phosphoproteome: Time Course of Response to Vasopressin (iTRAQ) (Hoffert et al., 2012)7. Rat Medullary Thick Ascending Limb Phosphoproteome: Response to PTH/AVP/Glucagon/Calcitonin (Gunaratne et al., 2010)8. Phosphoproteome: PKA Double Knockout in mpkCCD (Isobe et al., 2017)9. IMCD Phosphoproteome with Acute Lithium Treatment (Trepiccione et al., Kidney Int., 2014)10. Phosphoproteome: PKA Catalytic Alpha Knockout in mpkCCD (Raghuram et al., 2020)11. Phosphoproteome: PKA Catalytic Beta Knockout in mpkCCD (Raghuram et al., 2020)12. Phosphoproteome: Myosin Light Chain Kinase Knockout in mpkCCD (Isobe et al., 2020)13. Phosphoproteome: CAMK2-delta in mpkCCD (Park et al., 2023)14. Epidermal Growth Factor Response in Rat Inner Medullary Collecting Duct15. Epidermal Growth Factor (EGF) Signaling Network in Rat IMCD16. Inner Medullary Collecting Duct Phosphotyrosinome (Zhao et al., Am.J.Physiol., 2012) 17. Protein Kinase A Substrates 18. IMCD Kinase Substrate Database (Bradford et al., Am.J.Physiol., 2014)19. Renal Cortical Membrane Phosphoproteome Database (Feric et al., Am.J.Physiol., 2011)20. Collecting Duct Phosphoproteome Database (Hoffert et al., PNAS, 2006)<br><br><br>