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Genome wide CRISPR screening identifies TMEM106B as proviral host factor for SARS-CoV-2

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NIAID Data Ecosystem2026-03-12 收录
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We performed a genome-wide CRISPR knockout screen to identify human genes required for SARS-CoV-2 infection. Overall design: Human Huh7 CRISPR-Cas9 perturbed cells were infected with SARS-CoV-2 at low and high stringency, and cells were collected for genomic DNA isolation 18 or 41 days post-infection

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2021-01-05
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