RNA-seq of LPS-challenged microglial cell treatment with TOP1 inhibitor. RNA-seq of LPS-challenged microglial cell treatment with TOP1 inhibitor

This dataset contains the RNA-seq data generated to investigate the mechanism of TOP1 inhibitor topotecan (TPT)'s role of anti-inflammation in microglial. RNA from mouse microgial cells, cells with LPS treatment to induce inflammation, and cells with LPS and TPT treatment were harvest and processed with polyA-tail enrichment RNA library preparation.