Lecanemab binds to transgenic mouse model-derived amyloid-β fibril structures resembling Alzheimer´s disease type-I, type-II and Arctic folds

Immunogold electron microscopy of lecanemab-bound amyloid-beta fibrils from transgenic mouse models of Alzheimer's disease Mouse models: tg-APPArcSwe APP23 tg-APPSwe APP/PS1 ARTE10 tg-SwDI All micrographs utilized for the co-localization analysis of lecanemab binding to amyloid-β fibrils are compiled in the file ig_tem_mic_lecanemab_Ab_fibrils_coloc.tar. All electron micrographs presented in Figure 1 of the manuscript can be accessed in the file ig_tem_mic_lecanemab_Ab_fibrils_Fig1.tar.