CanineHD 230 K BeadChip data from Miniature Dachshunds

Abstract

Several hundred disease-causing mutations are currently known in domestic dogs. Breeding management is therefore required to minimize their spread. Recently, genetic methods such as direct-to-consumer testing have gained popularity; however, their effects on dog populations are unclear. 
A variant in the RPGRIP1 gene is a causative element associated with cone-rod dysplasia 1 (cord1) and progressive retinal atrophy (PRA) in dogs, notably purebred Miniature Dachshunds (DHMs).
Here, we aimed to evaluate the influence of genetic testing on the frequency of mutations responsible for canine PRA and assess the changes in the genetic structure of a DHMs population from Japan.
To evaluate the influence of genetic testing on the frequency of mutations causing canine degenerative myelopathy and changes to genetic structure in the Pembroke Welsh corgi population from Japan, 117 dogs were genotyped.
Weir and Cockerham population differentiation (FST) based on genome-wide single-nucle..., , Illumina's Canine 230K Consortium BeadChip data from 503 dogs. The breed is DSM from Japan. Several software tools, such as PLINK ([https://www.cog-genomics.org/plink/](https://www.cog-genomics.org/plink/)), can be used to analyze the following datasets. A text editor like EmEditor can be used to open the files.

Dataset 1: 323 insured dogs
DSM_Ins_QC.ped
DSM_Ins_QC.map

Dataset 2: 180 dogs from pet shops
DSM_PS_QC.ped
DSM_PS_QC.map
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