Ternary complex structure of Cereblon-DDB1 bound to WIZ(ZF7) and the molecular glue dWIZ-1
收藏Protein Data Bank Japan2024-10-23 更新2026-04-19 收录
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Ternary complex structure of Cereblon-DDB1 bound to WIZ(ZF7) and the molecular glue dWIZ-1 Descriptor: (3S)-3-(5-{(1R)-1-[(2R)-1-ethylpiperidin-2-yl]ethoxy}-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione, 1,2-ETHANEDIOL, DNA damage-binding protein 1, ... Authors: Clifton, M.C, Ma, X, Ornelas, E. Deposit date: 2023-08-28 Release date: 2024-07-10 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (3.15 Å) Cite: A molecular glue degrader of the WIZ transcription factor for fetal hemoglobin induction. Science, 385, 2024
创建时间：
2023-08-28
