RNA-seq of PDAC patient-derived xenograft tumors
收藏NIAID Data Ecosystem2026-03-14 收录
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https://www.omicsdi.org/dataset/ega/EGAS00001007070
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资源简介：
We developed a novel antibody-drug conjugate (ADC), C6-EBET. To analyze mechanism of action of C6-EBET, we obtained bulk and single cell RNA-seq data of two patient-derived xenograft (PDX) models derived from pancreatic ductal adenocarcinoma (PDAC) patients. The two PDX models were treated with gemcitabine, C6-EBET or a non-targeting control ADC (HEL3-EBET), and then gene expression changes were analyzed with bulk RNA-seq. In addition, we characterized stromal cells of the two PDX models with scRNA-seq.EGA study EGAS00001007070
创建时间：
2023-03-16
