aThis model considers the sum of the two monokaryotic strains. αMeans that the enzymatic activity of this dikaryon is significantly different to both of its monokaryotic counterparts (p<0.05). βMeans
aThis model considers the sum of the two monokaryotic strains.αMeans that the enzymatic activity of this dikaryon is significantly different to both of its monokaryotic counterparts (pβMeans that the
Dual-targeting chromatin regulation and DNA damage repair signaling presents a promising avenue for cancer therapy. Applying rational drug design, we synthesized a potent dual-targeting small molecule