An integrated multiorgan feed-forward metabolic response exacerbates muscle wasting and lipid accumulation in human mitochondrial myopathies
收藏Alliance of Genome Resources2026-08-01 收录
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To investigate the systemic impact of muscle COX10 deficiency, a model of mitochondrial myopathy, we collected skeletal muscle, liver, and hypothalamus from end-stage (200d days) control and COX10 KO mice. Skeletal muscle, liver and hypothalamus were used for gene expression analyses. Libraries were sequenced with single-end 86 bps on an Illumina NextSeq500 sequencer
