Human Plasma Kallekrein in complex with 14W
收藏Protein Data Bank Japan2026-04-08 更新2026-04-19 收录
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https://pdbj.org/mine/summary/8a3q
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Human Plasma Kallekrein in complex with 14W Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, N-[(3-fluoranyl-4-methoxy-pyridin-2-yl)methyl]-3-(methoxymethyl)-1-[[4-[(2-oxidanylidenepyridin-1-yl)methyl]phenyl]methyl]pyrazole-4-carboxamide, ... Authors: McEwan, P.A. Deposit date: 2022-06-08 Release date: 2022-11-02 Last modified: 2026-04-08 Method: X-RAY DIFFRACTION (1.801 Å) Cite: Sebetralstat (KVD900): A Potent and Selective Small Molecule Plasma Kallikrein Inhibitor Featuring a Novel P1 Group as a Potential Oral On-Demand Treatment for Hereditary Angioedema. J.Med.Chem., 65, 2022
创建时间：
2022-06-08
