Effects of siRNA gene silencing on transcriptional responses of human synovial fibroblasts to TNF and IL-17A (RNA-seq Data 2)

TNF and IL-17A synergistic effects on gene expression after silencing CUX1, LIFR, STAT3, STAT4, ELF3 Human fibroblasts were transfected with siRNAs and then stimulated with TNF or TNF and IL-17A. RNA-seq Data 2 (n=192): 4 synovial fibroblast cell lines from patient tissues, 4 time points (0, 1, 6 and 16 hours), 2 stimulations (TNF (0.1 ng/mL); TNF (0.1 ng/mL) and IL-17A (1 ng/mL)), and 5 siRNAs (CUX1, LIFR, STAT3, STAT4, ELF3) --------------------------------------------------------- Authors state "We don't have the required patient consents to deposit the raw sequencing reads." Thus, this dataset is incomplete.