Natural variants in the G and H helices and C terminal extremity altering the sequence length of α-Hb.

The data were collected from HbVar, the globin gene server (http://globin.cse.psu.edu/globin/hbvar/).These different mutations led to an α-thalassemic phenotype more or less pronounced.*the production of α-globin is under the control of two genes α1 and α2-globin genes (HBA1 and HBA2 respectively)**Length expressed as number of amino-acid residues;del, deletion; ins, insertion;Natural variants in the G and H helices and C terminal extremity altering the sequence length of α-Hb.