Pde8a

ENCODES a protein that exhibits 3',5'-cyclic-AMP phosphodiesterase activity (ortholog); 3',5'-cyclic-GMP phosphodiesterase activity (ortholog); kinase binding (ortholog); INVOLVED IN cellular response to epidermal growth factor stimulus (ortholog); positive regulation of ERK1 and ERK2 cascade (ortholog); PARTICIPATES IN protein kinase A (PKA) signaling pathway; purine metabolic pathway; ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A

编码一种蛋白质，该蛋白质表现出3',5'-环磷酸腺苷磷酸二酯酶活性（同源物）；3',5'-环磷酸鸟苷磷酸二酯酶活性（同源物）；激酶结合（同源物）；参与细胞对表皮生长因子刺激的响应（同源物）；正调控ERK1和ERK2级联反应（同源物）；参与蛋白激酶A（PKA）信号通路；嘌呤代谢途径；与Bloom综合征（同源物）；结直肠癌（同源物）相关；与2,3,7,8-四氯二苯并-对二恶英；6-丙基-2-硫尿嘧啶；双酚A相互作用。