BackgroundCD4+CD25+FOXP3+ Regulatory T cells (Treg) play a central role in the immune balance to prevent autoimmune disease. One outstanding question is how Tregs suppress effector immune responses in

NIAID Data Ecosystem40

Regulatory T cells in the Tumor Microenvironment Display a Unique Chromatin Accessibility Profile (ATAC-Seq). Regulatory T cells in the Tumor Microenvironment Display a Unique Chromatin Accessibility Profile (ATAC-Seq)

免疫表观遗传学

调节性T细胞功能

Regulatory T cells (Tregs) are a suppressive CD4+ T cell population that limit the anti-tumor immune response. In this study, we analyzed the chromatin accessibility of Tregs in the murine tumor micro

NIAID Data Ecosystem00

Identification of covalent SUMO1 aceptor lysines

蛋白质SUMO化修饰

翻译后修饰位点

SUMO1 modified proteins were identified in a site specific manner.

NIAID Data Ecosystem40

Gene expression profiling of CD4+CD25+Foxp3+ regulatory T cells and CD4+CD25-Foxp3- T cells in the course of Plasmodium yoelii infection of BALB/c mice

感染免疫学

调节性T细胞功能

Gene expression profiling of CD4+CD25+Foxp3+ regulatory T cells and CD4+CD25-Foxp3- T cells in the course of Plasmodium yoelii infection of BALB/c mice

ChEBI2012-04-15 更新00

Protein SUMOylation is required for regulatory T cell expansion and function

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