Summary of NLP characteristics.
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aCalculated from full-width half-maximum (FWHM).
bMolar lipid-to-protein ratio.
cDMPC quantified using enzymatic assay. ApoLp-III quantified by UV-Vis spectroscopy.
dNumber of apoLp-III molecules determined by chemical cross-linking and SDS gel visualization.
eCalculated using experimentally determined DMPC/apoLp-III and apoLp-III/NLP.
fCalculated based on measured AFM diameters and DMPC molecular area, assuming 0.6 nm2/DMPC and 1 nm apoLp-III helix thickness. DMPC/NLP = π(rNLP-1)2/0.6.
gNLP-1 comprised of three main species: 25.4±0.9 nm, 30.5±1.1 nm, and 35.1±1.3 nm.
hNumber of DMPC lipid molecules per NLP was determined for aggregate of all NLP-1 sizes.
i25 nm, 30 nm, and 35 nm NLP-1 species hypothesized to contain 5, 6 and 7 apoLp-III molecules, respectively.
创建时间：
2010-07-19
