Deciphering the Pathophysiology of Chronic Fatigue Syndrome

Myalgic encephalomyelitis, also known as chronic fatigue syndrome or ME/CFS, is a complex and heterogeneous disease that severely impacts the health and quality of life of those afflicted. Several lines of evidence support the possibility that ME/CFS development may involve a heritable component. In this pilot study, 42 cases that meet the diagnostic criteria of ME/CFS and 38 healthy controls were consented into this study. The goal of this study was to identify candidate polymorphisms that can be used for a large multi-center screening study.]]>
Subjects who meet the 1994 Fukuda et al. criteria for chronic fatigue syndrome1 as well as 2003 Carruthers et al. criteria for myalgic encephalomyelitis.]]>