Unrestricted SUMOylation drives lymphomagenesis
收藏NIAID Data Ecosystem2026-03-13 收录
官方服务:
资源简介:
Unrestricted SUMOylation drives lymphomagenesis Overall design: Unrestricted SUMOylation drives lymphomagenesis
应用场景:
创建时间:
2022-01-29
相关数据集
Actionable loss of SLF2 drives B-cell lymphomagenesis and impairs the DNA damage Response
The DNA damage response (DDR) acts as a barrier to malignant transformation and is often impaired during tumorigenesis. Exploiting the impaired DDR can be a promising therapeutic strategy; however, th
NIAID Data Ecosystem100
Irradiation Promotes V(D)J Joining and RAG-Dependent Neoplastic Transformation in SCID T-Cell Precursors
Defects in the nonhomologous end-joining (NHEJ) pathway of double-stranded DNA break repair severely impair V(D)J joining and selectively predispose mice to the development of lymphoid neoplasia. This
PubMed Central60
Functional Proteomics Study Reveals SUMOylation of TFII‑I is Involved in Liver Cancer Cell Proliferation
SUMOylation has emerged as a new regulatory mechanism for proteins involved in multiple physiological and pathological processes. However, the detailed function of SUMOylation in liver cancer is still
NIAID Data Ecosystem30
Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis [ChIP-Seq]
The c-myc proto-oncogene product, Myc, is a transcription factor that binds thousands of genomic loci. Recent work suggested that rather than up- and down-regulating selected groups of genes, Myc targ
NIAID Data Ecosystem100
Table_1_Savior Siblings Might Rescue Fetal Lethality But Not Adult Lymphoma in Irf2bp2-Null Mice.xlsx
Interferon regulatory factor 2 binding protein 2 (Irf2bp2), a co-repressor of Irf2, is required for fetal hepatic erythropoiesis through the expansion of erythromyeloid progenitors. Mice with germline
NIAID Data Ecosystem40



