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Age-associated dysregulation of peroxisomal matrix protein importing impairs intestinal stem cell differentiation and gut functions

Name: Age-associated dysregulation of peroxisomal matrix protein importing impairs intestinal stem cell differentiation and gut functions
Creator: West China Hospital, Sichuan University
Published: 2024-10-01T10:24:20+08:00

integrated proteome resources2026-02-07 收录

细胞衰老机制

肠道干细胞

数据链接：

https://www.iprox.cn/page/project.html?id=IPX0009860000 数据链接链接失效反馈

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资源简介：

Age-associated dysregulation of peroxisomal matrix protein importing impairs intestinal stem cell differentiation and gut functions

应用场景：

提供机构：

West China Hospital, Sichuan University

创建时间：

2024-10-01

细胞衰老机制

DNA损伤响应

For studing dynamic transcriptome profiling in DNA damage-induced cellular senescence and transient cell-cycle arrest, samples were treated with the DNA-damaging agent bleomycin at 0 ug/ml, 2 ug/ml an

NIAID Data Ecosystem40

Gene expression profile of Wharton-jelly mesenchymal stem cells at 12th in vitro expansion cycle compared to Wharton-jelly mesenchymal stem cells at 4th in vitro expansion cycle. Homo sapiens

干细胞转录组学

细胞衰老机制

Mesenchymal stem cells (MSCs) are generally considered the main tool box for cell-based therapies and compared to embryonic stem cells (ESCs), MSCs exhibit many advantages. It has been shown that UC m

NIAID Data Ecosystem20

Additional file 1: Table S1. of Sox9 transcriptionally regulates Wnt signaling in intestinal epithelial stem cells in hypomethylated crypts in the diabetic state

表观遗传学

肠道干细胞

qRT-PCR primer sequences. Table S2. Bisulfite-sequencing primer sequences. Table S3. Summary of methylation enrichment peaks (MEPs) promoter regions. Table S4. Unsupervised hierarchical clustering ana

Figshare2017-03-10 更新10

Transcriptional and epigenetic landscape of the mouse intestine during aging identifies key molecular drivers of aging -associated dysfunctions and diseases. [Total RNA-seq - Lgr5]. Transcriptional and epigenetic landscape of the mouse intestine during aging identifies key molecular drivers of aging -associated dysfunctions and diseases. [Total RNA-seq - Lgr5]

衰老生物学

肠道干细胞

Aging is a complex multifactorial process leading to the loss of tissue/organ functionality and to an increase in disease risk. Aging-related intestinal dysfunctions include loss of barrier integrity,

NIAID Data Ecosystem20

Sox9-eGFP cell sorted intestinal cells. Mus musculus

肠道干细胞

细胞亚群分析

The different cell populations of intestinal crypts were sorted based on the expression of Sox9eGFP expression. Overall design: Separation of intestinal crypts into subpopulations

NIAID Data Ecosystem10

Age-associated dysregulation of peroxisomal matrix protein importing impairs intestinal stem cell differentiation and gut functions

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