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Tracing the Origin and Evolution of Mycophenolic Acid Biosynthesis in Fungi

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP357708
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Mycophenolic acid (MPA) is a natural meroterpenoid well documented for inhibiting inosine monophosphate dehydrogenase involved in de novo purine synthesis. Because of this critical metabolic effect in human T and B lymphocytes, MPA is used as an immunosuppressive agent, mostly in the framework of solid organ transplantations.
创建时间:
2024-05-29
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