Protection level induced by immunization with rSm22.6 plus Freund’s adjuvant in Balb/c mice previously infected/treated.

aWorm burden recovered from mice immunization with one, two or three doses. For each vaccinated group: n = 10 mice. Comparison between total worm burden recoveredb or numbers of eggs per gram of intestinec from IT/Sm22.6 group and IT/Saline control group, which received the same number of immunization doses and were challenged with 50 S. mansoni LE strain cercariae. NS = not significant. ND = not determined. Protection level induced by immunization with rSm22.6 plus Freund’s adjuvant in Balb/c mice previously infected/treated.