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Pseudomonas aeruginosa DNA gyrase B 24kDa ATPase subdomain complexed with EBL2888

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Protein Data Bank Japan2024-02-07 更新2026-03-28 收录
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https://pdbj.org/mine/summary/7ptg
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资源简介:
Pseudomonas aeruginosa DNA gyrase B 24kDa ATPase subdomain complexed with EBL2888 Descriptor: 2-[[3,4-bis(chloranyl)-5-methyl-1H-pyrrol-2-yl]carbonylamino]-4-[(1S)-1-phenylethoxy]-1,3-benzothiazole-6-carboxylic acid, DNA gyrase subunit B Authors: Cotman, A.E, Zega, A, Zidar, N, Ilas, J, Tomasic, T, Masic, L.P, Mundy, J.E.A, Stevenson, C.E.M, Burton, N, Lawson, D.M, Maxwell, A, Kikelj, D. Deposit date: 2021-09-27 Release date: 2022-10-05 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa. J.Med.Chem., 66, 2023
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2021-09-27
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