Gsta4

ENCODES a protein that exhibits organic cyclic compound binding; toxic substance binding; glutathione transferase activity (ortholog); INVOLVED IN cellular response to lithium ion; response to herbicide; response to nicotine; PARTICIPATES IN glutathione conjugation pathway; glutathione metabolic pathway; phase I biotransformation pathway via cytochrome P450; ASSOCIATED WITH Experimental Diabetes Mellitus; Experimental Liver Cirrhosis; Liver Injury; FOUND IN cytosol (ortholog); mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; (E)-4-hydroxynon-2-enal; (S)-nicotine

编码一种具有有机环状化合物结合、毒性物质结合、谷胱甘肽转移酶活性（同源）特性的蛋白质；参与细胞对锂离子、除草剂和尼古丁的反应；在谷胱甘肽结合途径、谷胱甘肽代谢途径以及通过细胞色素P450介导的I相生物转化途径中发挥作用；与实验性糖尿病、实验性肝硬化和肝损伤相关；存在于细胞质（同源）和线粒体（同源）中；与（+）五味子素B、(E)-4-羟基壬-2-烯醛和(S)-尼古丁相互作用。